Honorary members named in June 2015 (Paris meeting):
Muriel Davisson is an American neuroscientist who developed the Down syndrome mouse model Ts65Dn.
In 1959 she graduated from Pemetic High School in Southwest Harbor, Maine. She holds Ph. D. from Penn State University (1969). She was director of Genetic Resource Science at Jackson Laboratory. Her work concentrates on developing mouse models of human genetic disorders including Down syndrome. She is now semiretired from Jackson Laboratory. Her mice was used in number of Down syndrome studies leading to promising drug therapies. In 2002 the National Down Syndrome Society named her "Researcher of the Year."
Jesús Flórez is Doctor of Medicine and Surgery (Spain), Doctor of Pharmacology (Ph.D.) (USA), and Professor of Pharmacology at the University of Cantabria.
He initiated his scientific career as a professor and researcher in the field of Pharmacology, however, his work in the field of Down syndrome has been dedicated to investigate the neurobiological aspects of intellectual disability in animal models of Down syndrome and analyze possible beneficial pharmacological products, the results of which have been published in prestigious international journals. He has taught more than 500 lectures and classes in courses, symposia, conferences, conferences dedicated to Down syndrome in all Spanish provinces, all Latin American countries, USA, France, Belgium, Germany, United Kingdom, Italy, or Sweden. He is president of the Fundación Iberoamericana Down21 and directs three web pages: Channel Down21 (www.down21.org), DownCiclopedia (www.downciclopedia.org) and Down Syndrome: Adult Life (www.sindromedownvidaadulta.org/). He is Scientific Advisor of the Down Syndrome Foundation of Cantabria and director of the magazines Revista Síndrome de Down (http://revistadown.downcantabria.com/) and Revista Virtual Canal Down21 (http://www.down21.org/revista-virtual).
He has authored eight books and several hundred articles, both scientific and informative, on intellectual disability and Down syndrome. The most recently published are: "Down Syndrome: Neurobiology, Neuropsychology, Mental Health" (2015) and "Down Syndrome." Communicate the news: The first therapeutic act "(2017).
Prof. Flórez has received several awards for his research and personal commitment on Down syndrome and intellectual disability, among which Christian Pueschel Award for Scientific Research in Down Syndrome, awarded by the National Down Syndrome Congress, USA in 2005, the International Award for dedication to Down Syndrome, 1st Ibero-American Congress on Down Syndrome, Buenos Aires (2007), Gold Medal, Official Physicians Association of Cantabria (2007), Gold Medal, Spanish Red Cross (2008), First Prize "Family and Disability" awarded to the Flórez Troncoso family by the Chair "Family and Disability", Universidad Pontificia de Comillas, Madrid (2013), Exceptional Meritorious Service Award, National Down Syndrome Congress, USA (2015) or the Award for the Best Scientific Career in Pharmacology. Spanish Society of Pharmacology (2015).
May Lou Oster-Granite
Honorary members named in June 2017 (Chicago meeting):
Born in 1925, in Montenils (Seine-et-Marne), France, Marthe Gautier is a medical doctor and researcher in Paris. In 1955, she defended her thesis in pediatric cardiology under the direction of Robert Debré, in charge of pediatric in France at that time. Professor Debré offered her a fellowship for one year at Harvard University where she acquired knowledge and skills in pediatric cardiology and cell culture.
When returned to Paris, Gautier accepted a position at the Trousseau Hospital, in Raymond Turpin’s team where she founded the first laboratory in France for cell culture.
Marthe Gautier is best known for her work on pediatric and for her role in the discovery of the cause of Down syndrome. This discovery was published, in 1959, in the proceedings of the French Academy of Sciences. In addition to Trousseau Hospital, Gautier worked at INSERM and at Kremlin-Bicêtre Hospital with Daniel Alagille.
Marthe Gautier has received many awards in recognition of her important work. She received, in 1971, the Winslow Price and, in 1975, the Monthyon Price of the French Academy of Sciences. In 2014, she was awarded the Grand Prize of Human Genetics from the French Society of Human Genetics and the French Federation of Human Genetics. Gautier received the insignia of the Legion of Honour, the premier order of the French republic in 2014.
Marthe Gautier is currently in retirement but she is still highly active in science, art, and history. In February 2017, she co-founded Ethics & Integrity, a non-profit organization, to promote research ethics and women in sciences.
Patricia (Pat) Jacobs was born in London in October 1934. Her father worked for the I.C.I. Nobel Explosives division and on the outbreak of the Second World War her family moved north to the west coast of Scotland. Pat was educated in Scotland and went to study botany at St Andrew’s University, but transferred to Zoology. Pat graduated in 1956 with a first-class honours degree and her undergraduate thesis on the meiotic process in Mantis religiosa was subsequently published in the Journal of Genetics, with her mentor Professor H.G. Callan, a reknowned cytogeneticist. Pat went straight into a research post, without undertaking a PhD. She first worked as a mouse geneticist for Dr Kathleen Stein at Mount Holyoke College, Massachusetts, USA. On returning to UK in 1957 she joined the UK Medical Research Council Clinical Effects of Radiation Research Unit, in Edinburgh, under the direction of Michael Court Brown. This was an immensely productive period and by 1966 not only had she been made a staff scientist, she was also awarded a DSc from St Andrew’s University for her outstanding work on human cytogenetics. Pat spent a sabbatical year with Dan Lindsley at UCSD in 1970-71, and moved to the University of Hawaii in 1972 for another outstanding period of discovery. In 1988, via a two years at Cornell University Medical School, she returned to UK to take up a post, until she retired, at the Wessex Regional Health Authority in Southampton, UK. Pat is a pioneer of cytogenetics, specifically human cytogenetics. She has worked at the absolute forefront of knowledge and made enough seminal discoveries for many careers, let alone one person’s. These include first identifying the chromosomal make up of Klinefelter’s syndrome, first identifying an XXX female, and three months after the Gautier, Turpin, Lejeune finding of trisomy 21 in Down syndrome, publishing her own corroborative study. That was just 1959 alone…
Many many more discoveries, Fellowship of the Royal Society, election to the US National Academy of Science, many prizes and medals have been deservedly bestowed on Pat, and in 2017 she was awarded Lifetime Membership of the T21 Research Society. Pat is a far-sighted, meticulous, insightful scientist who has made an extraordinary contribution to our understanding of biology and of what it means to be human.