Charles J. Epstein Award for Early-Stage Investigators

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 Charles J. Epstein Award for Early-Stage Investigators

Sponsored by the National Down Syndrome Society (NDSS) in collaboration with the Trisomy 21 Research Society (T21RS)

The Charles J. Epstein Award honors an exceptional early-stage independent researcher whose work shows outstanding dedication and potential to advance science in the field of Down syndrome. Dr. Epstein pioneered the gene-dosage hypothesis for Down syndrome and developed the first mouse models of trisomy 21, establishing the mechanistic foundation for understanding how extra copies of chromosome 21 genes disrupt development and cognition. This biennial award highlights the strong partnership between NDSS and T21RS in supporting the next generation of Down syndrome researchers.

 Aim   

To recognize and promote early-career scientists making significant contributions toward understanding and improving the lives of individuals with Down syndrome.

 Eligibility / Requisites

  • Must be a current member of T21RS.
  • Classified as an early-stage investigator (received terminal degree ≤ 10 years ago and/or not yet promoted to Associate Professor or equivalent).
  • Must attend the T21RS International Conference in person to receive the award.
  • Self-nominations are not accepted.
  • Required materials:
    • One or more letters of nomination
    • Current CV
  • Open to candidates of all nationalities, backgrounds, and beliefs.

 Evaluation Criteria

  • Scientific excellence and originality of research
  • Demonstrated commitment to Down syndrome science
  • Evidence of leadership potential and future impact
  • Applications are reviewed in February 2026  by a joint NDSS–T21RS ad hoc committee

 Award and Recognition

  • Prize: USD $5,000 cash award + personalized plaque
  • Conference Benefits: Free registration and invited presentation at the T21RS International Conference
  • Post-award Requirement: Awardee provides a short research summary within 6 months for sharing through NDSS and T21RS networks

SUBMISSION DEADLINE: January 31, 2026