T21RS biennial International Conference is instrumental in promoting scientific exchanges, maximizing resource use and defining the most promising research at the basic, translational and clinical levels. The rapid pace of progress that has taken place in the last few years demands effective communication between scientists and clinicians working in the field.
The 1st International Conference of the T21RS was held in Paris in June 2015 with the motto “Changing paradigms in Down syndrome” attracting scientists, clinicians and members of associations and foundations. The Second International Conference of the T21RS “Paving the way for therapy” was held in Chicago, June 8-11, 2017 and the Third, “Science for future Therapy” was held in Barcelona in June 6-9, 2019. In June 8-10 2021, it was hels the T21RS Virtual Conference using an online platform. Cutting edge results in neuroscience, neurology, model systems, psychology, cancer, and molecular and pharmacological approaches demonstrate the compelling interest and continuing advance in all aspects of understanding and ameliorating conditions associated with trisomy 21.
4th T21RS International Conference 2022
The 4th T21RS International conference will be held in Long Beach, California on June 9-12 2022. We are working on having an exciting scientific program and unforgettable Science & Society symposium to establish the dialog between researchers and the families and Down syndrome associations. Hope to see all of you there!
Abstract submission is open!
The Scientific Program Committee is requesting abstracts representing research in basic, clinical, and translational research in Down syndrome, ranging from molecular biology to human research, and especially topics that bridge scientific disciplines. We welcome abstracts from multiple disciplines, including, but not limited to, Down syndrome related disorders, mechanisms underlying developmental challenges, genomics, neuroscience, pharmacological research, new technologies, or sociological aspects (see Themes below).
Deadline for submissions: April 15, 2022
This call will also ask abstract submitters to select categories of participation in our meeting, which include 2 broad categories (senior and junior investigator opportunities):
- Senior Investigator
- Poster abstract only
- Poster abstract and consideration for selection in a nanosymposium (see information below – note these will be limited)
- Junior Investigator (researchers within 5 years of a completing an MD/PhD) poster abstracts will be:
- automatically entered into a poster judging contest with a cash reward
- may be selected for a data blitz talk
- can be selected for a travel award upon request
- can be selected for a childcare award upon request
Requirements for abstract submission
Authors may submit one abstract as presenting author (although an author can co-author multiple abstracts but not as presenting author). Abstracts must be in topics related to the theme of the conference, should be original and unpublished and at least one author should be a member of T21RS.
Submission Portal: The abstract can be sent through the online platform. Please click on the button below.
We recommend that you prepare your abstract in a text document and then paste it in the corresponding place at the time of submission.
Authorship – there is no limitation on authors but the presenting author must be identified and is allowed to submit only one abstract.
All authors must agree with the content of the abstract.
The presenting author, at minimum, is required to register for and attend the meeting.
Title –should not exceed 50 words.
The title of the work must be related to the abstract.
Body of the abstract – The abstract must have a minimum of 150 and a maximum of 300 words Please check the number of characters before sending. Before sending, make sure that all the information you want is contained in the summary.
The abstract should be presented with subheadings that include introduction, methods, results, conclusions and funding support. Guidance is below:
Introduction: “What is known about the subject and what is missing?”
In one or two sentences.
Methods: “How was the study conducted?”
Briefly describe: the type of study, context, population and sample, dependent / independent variables, instruments used, data analysis should be according to the type of the variable used / method, etc. Please use the Arrive guidelines in reporting research methods involving the use of animals (see https://www.t21rs.org/preclinical-committee/)
Results: “What was the outcome?”
Describe the major outcomes of the study.
Conclusions: “What is the “take home message” from the work presented?”
The conclusions must be supported by the results.
Funding support: Identify the source of financial support for the study if present.
Information for Nanosymposia
Poster presenters with related topics have the opportunity form a Nanosymposium, which will be a short 30-min session, with a maximum of three speakers.
If you are interested in organizing a Nanosymposium, please identify in your application the one or two accompanying poster titles and presenting authors that should be included. Those posters will also have neighboring slots in the poster area.
Information for Junior Investigator Data Blitz Presentations
A data blitz is a series of 7-minute talks with 3 min discussion and are intended to a fast paced, dynamic overview of many areas of research by junior investigators presented at the poster sessions. The scientific program committee will select abstracts based on quality and to ensure diversity and invite authors to present.
Information for Junior Investigator Poster Competition
During the first two days of the conference, posters and Data Blitz presentations will be judged by senior members of T21RS based on the highest scientific excellence, presented in the most effective way.
During the Gala Dinner, on June 11th, 2022, we will announce the 3 poster winners, one from each category (undergraduate, graduate, and postdoctoral). In addition to a cash prize, free membership in T21RS for one year, free registration for the next in person meeting will be provided and each of the winners will be featured on the T21Rs website.
Theme 1. Genomic and epigenetic mechanisms: Genetics, genomics, epigenetics, other -omics (transcriptome, metabolome, proteome, exposome, single-cell etc.), 3D genome organisation, multiomic modelling
Theme 2. Molecular and Cellular Mechanisms: Neurobiological, immunological, metabolism, synaptic mechanisms, plasticity, neuronal networks, etc
Theme 3. Experimental models: Animal models, cellular models, organoids, stem cells and reprogramming, etc.
Theme 4. Cognition and Behavior: Clinical and preclinical studies on cognition and behaviour, intellectual disability, language, behavior, emotion, executive functions, sex-specific differences, neuropsychological evaluation tools
Theme 5. Neurodegeneration and Ageing: Alzheimer disease in Down syndrome, neuropathology, immunosenescence, cognitive decline, etc.
Theme 6. Neurodevelopment: Neuropathology, neurogenesis, cell proliferation and differentiation, synaptogenesis, nervous system patterning, etc.
Theme 7. Co-occurring Illnesses: Cancer/ leukemia, psychiatric disorders, metabolic disorders, sensory disorders, cardiovascular diseases, etc.
Theme 8. Therapeutic intervention: Pharmacological/non-pharmacological interventions, neurotherapy, preclinical drug development, experimental therapeutics, clinical trials
Theme 9. Diagnosis and Evaluation: Biomarkers, neuroimaging, outcome measures
Theme 10. Other