T21RS biennial International Conference is instrumental in promoting scientific exchanges, maximizing resource use and defining the most promising research at the basic, translational and clinical levels. The rapid pace of progress that has taken place in the last few years demands effective communication between scientists and clinicians working in the field.

The 1st International Conference of the T21RS was held in Paris in June 2015 with the motto “Changing paradigms in Down syndrome” attracting scientists, clinicians and members of associations and foundations. The Second International Conference of the T21RS “Paving the way for therapy” was held in Chicago, June 8-11, 2017 and the Third, “Science for future Therapy” was held in Barcelona in June 6-9, 2019. In June 8-10 2021, it was hels the T21RS Virtual Conference using an online platform. The Forth International Conference was held in Long Beach (California) in June 9-12, 2022. Cutting edge results in neuroscience, neurology, model systems, psychology, cancer, and molecular and pharmacological approaches demonstrate the compelling interest and continuing advance in all aspects of understanding and ameliorating conditions associated with trisomy 21.
6th T21RS International Conference 2026
We are delighted to announce that the 6th International Conference of the Trisomy 21 Research Society will take place in Denver, Colorado, from June 17 to June 20, 2026. This international conference provides a unique platform to discuss research into Down syndrome. The conference in Colorado will take place at the Grand Hyatt downtown Denver, located just a short drive from the Rocky Mountains, with access to lots to see and do in Colorado (see https://www.colorado.com/things-to-do).
As president and president elect, and on behalf of the Organizing Committee, we hope you will attend this conference.
The mission of T21RS is to promote basic and applied research on Down syndrome, stimulate translational research and apply new scientific knowledge to improve the quality of life for people with Down syndrome. The conference in Denver will bring together benches to bedside scientists and clinicians. In 2026, you will see special emphasis on trainees, with workshops and activities geared towards the future of Down syndrome research! The conference in Rome 2024 brought together close to 500 scientists from many countries and we hope to expand the reach of the society to include scientists in additional countries this time around.
The Local Organizing Committee is chaired by Dr. Lotta Granholm at CU Anschutz Medical Campus. The conference is co-organized by the Linda Crnic Institute for Down Syndrome and the Global Down Syndrome Foundation, with many scientists from the seven universities in Colorado contributing. The Program Committee is chaired by Dr. Kelly Sullivan at CU Anschutz, who will be working closely with Dr. Granholm to organize this conference.
We hope to meet you all in Denver in June 2026!