In 2019, T21RS kicked off a Young Investigators Program, with many different activities (http://t21rs2019.com/young-investigator-programme/). Young investigators are an integral part of the T21RS Conference and T21RS installed a variety of measures to ensure that their participation is made as fruitful as possible. The young investigators had the opportunity to apply for travel grants, join the volunteers program, attend focused interest sessions, participate in the “Meet the Scientist” session or even visit during one month a research lab investigating on Down syndrome in Spain to learn new techniques or simply get to know the lab and discuss about job opportunities. They had plenty of opportunities for their career development.